Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 7/20 | 0.44 |
| ▸ | GSK3A | P49840 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306506 | 0.72 | MAPK1 (0.71) | MAPK1GSK3BGSK3AGAAPOLB | |
| SCHEMBL1730607 | 0.71 | MAPK1 (0.58) | MAPK1GSK3BGSK3AGAAHPGD | |
| SCHEMBL10438652 | 0.69 | MAPK1 (0.60) | MAPK1GSK3BGSK3AGAAPOLB | |
| SCHEMBL12660977 | 0.68 | MAPK1 (0.65) | MAPK1GSK3BGSK3AGAAKAT2B | |
| SCHEMBL26558990 | 0.66 | MAPK1 (0.62) | MAPK1GSK3BGSK3AGAAKAT2B | |
| SCHEMBL8208644 | 0.66 | MAPK1 (0.56) | MAPK1GSK3BGSK3AGAAPOLB | |
| SCHEMBL13310390 | 0.65 | MAPK1 (0.74) | MAPK1GSK3BGSK3AGAAPOLB | |
| SCHEMBL10607179 | 0.63 | MAPK1 (0.71) | MAPK1GSK3BGSK3AGAAPOLB | |
| SCHEMBL12211923 | 0.63 | MAPK1 (0.52) | MAPK1GSK3BGSK3AGAAPOLB | |
| SCHEMBL1722780 | 0.62 | GSK3B (0.71) | MAPK1GSK3BGSK3AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912580-A2 | 5H-PYRROLO(3',4':5,6)(1,4)DITHIINO(2,3-C)-(1,2,5)THIADIAZOLE-5,7(6H)-DIONE, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1999-05-06 | — | — | EP | claimed |
| WO-1998001452-A2 | 5H-PYRROLO(3',4':5,6)(1,4)DITHIINO(2,3-C)-(1,2,5)THIADIAZOLE-5,7(6H)-DIONE, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-01-15 | — | — | WO | claimed |
| US-5633219-A | 5H-pyrrolo(3',4':5,6)(1,4)dithiino(2,3-C)(1,2,5)thiadiazole-5,7(6H)-dione, compositions containing them and their use as antimicrobial and marine antifouling agents | THE DOW CHEMICAL COMPANY (US) | 1997-05-27 | — | — | US | claimed |
| US-5633219-A | 5H-pyrrolo(3',4':5,6)(1,4)dithiino(2,3-C)(1,2,5)thiadiazole-5,7(6H)-dione, compositions containing them and their use as antimicrobial and marine antifouling agents | THE DOW CHEMICAL COMPANY (US) | 1997-05-27 | — | — | US | disclosed |