Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7396934 | 0.99 | HSD11B1 (0.43) | HSD11B1SIGMAR1FAAHHTR2CHTR3A | |
| SCHEMBL8464871 | 0.85 | HTR4 (0.52) | SIGMAR1HTR2CHTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL7400600 | 0.83 | HTR2C (0.46) | SIGMAR1HTR2CHTR3AHTR3EHTR3B | |
| SCHEMBL8323434 | 0.82 | HTR4 (0.57) | SIGMAR1HTR2CHTR3AHTR3EHTR3B | |
| SCHEMBL8319643 | 0.82 | HTR4 (0.44) | SIGMAR1HTR2CHTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL7448294 | 0.81 | HTR2C (0.58) | SIGMAR1HTR2CHTR3AHTR3EHTR3B | |
| SCHEMBL8321696 | 0.80 | HTR4 (0.47) | SIGMAR1HTR2CHTR3AHTR3EHTR3B | |
| SCHEMBL7392992 | 0.79 | SLC6A2 (0.40) | SIGMAR1HTR2CHTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL9014559 | 0.78 | SLC6A2 (0.42) | SIGMAR1HTR2CHTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL27347139 | 0.74 | DRD2 (0.55) | SIGMAR1HTR2CHTR3AHTR4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604494-B1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-28 | — | — | EP | claimed |