Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319315 | 0.86 | CYSLTR1 (0.52) | CYSLTR1GPBAR1 | |
| SCHEMBL8321628 | 0.79 | CYSLTR1 (0.37) | CYSLTR1MAOAMAOBGPBAR1 | |
| SCHEMBL8321585 | 0.77 | CYSLTR1 (0.38) | CYSLTR1GPBAR1 | |
| SCHEMBL8145110 | 0.77 | MAOA (0.62) | MAOAMAOB | |
| SCHEMBL8318947 | 0.76 | CYSLTR1 (0.39) | CYSLTR1GPBAR1 | |
| SCHEMBL8320770 | 0.76 | CYSLTR1 (0.49) | CYSLTR1GPBAR1 | |
| SCHEMBL8143288 | 0.74 | MAOA (0.45) | MAOAMAOBGRM5 | |
| SCHEMBL8140542 | 0.73 | MAOB (0.55) | MAOAMAOB | |
| SCHEMBL8145824 | 0.70 | MAOB (0.63) | MAOAMAOB | |
| SCHEMBL8144813 | 0.70 | CYSLTR1 (0.66) | CYSLTR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885987-A | ANTIHISTAMINE AGENT FOR TREATING ASTHMA, ANTILEUKOTRIENE AGENT, ANTIALLERGENS | KOWA CO., LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5756518-A | EXHIBITS ANTILEUKOTRIENIC ACTION AND ANTIHISTAMINIC ACTION; IS USEFUL IN TREATMENT OF ASTHMA | KOWA CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |