Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | PRKCB | P05771 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320632 | 0.94 | CAMK2D (0.44) | CAMK2DKDRPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL8315530 | 0.83 | CAMK2D (0.43) | CAMK2DKDRPRKCBPRKCAPRKCH | |
| SCHEMBL8316483 | 0.77 | CAMK2D (0.51) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8319189 | 0.75 | PRKCB (0.49) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8316034 | 0.74 | CAMK2D (0.45) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8317050 | 0.74 | CAMK2D (0.45) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8317078 | 0.74 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8317298 | 0.74 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL1155976 | 0.73 | KDR (0.63) | KDRGSK3BFLT3PLK4AURKA | |
| Hydrochloric Acid SCHEMBL8318720 | 0.73 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | disclosed |