Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | SCN2B | O60939 | 2/20 | 0.32 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831161 | 0.92 | S1PR3 (0.32) | MOGAT2CYP2C9SCN9ASCN5ASCN1A | |
| SCHEMBL831314 | 0.90 | SCN9A (0.36) | MOGAT2CYP2C9SCN9ASCN5AMGAT2 | |
| SCHEMBL833395 | 0.90 | CDK2 (0.33) | MOGAT2CYP2C9CDK2LMNAMEN1 | |
| SCHEMBL831390 | 0.89 | CYP2C8 (0.39) | MOGAT2CYP2C9SCN9ASCN5AMGAT2 | |
| SCHEMBL832279 | 0.86 | PTGDR2 (0.36) | MOGAT2CYP2C9SCN9ASCN5AMGAT2 | |
| SCHEMBL8860573 | 0.86 | CYP2C9 (0.31) | MOGAT2CYP2C9SCN9ASCN5ASCN1A | |
| SCHEMBL12665276 | 0.86 | CYP2C8 (0.38) | CDK2LMNAMEN1KMT2AHPGD | |
| SCHEMBL12665810 | 0.86 | LMNA (0.35) | CDK2LMNAMEN1KMT2AHPGD | |
| SCHEMBL13905361 | 0.83 | CYP2C8 (0.38) | MOGAT2CYP2C9SCN9ASCN5AMGAT2 | |
| SCHEMBL831856 | 0.83 | OPRM1 (0.38) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143305-B2 | 2,3-substituted indole derivatives for treating viral infections | SCHERING CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110033417-A1 | 2,3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | MERCK SHARP & DOHME CORP. | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110033417-A1 | 2,3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | IDO2, IDO1, IRF3 | MOGAT2 2114/4885CYP2C9 2171/4885SCN9A 3807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.