Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109724 | 1.00 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL17134067 | 1.00 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL28530493 | 0.89 | CTSL (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL28127816 | 0.82 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL3725357 | 0.82 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| Bromobenzene SCHEMBL28232899 | 0.81 | CYP2C19 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL6815084 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL6815081 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL17008402 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL749086 | 0.78 | C1S (0.56) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015178847-A1 | PROCESS FOR THE PREPARATION OF CHIRAL AMINES BY ASYMMETRIC HYDROGENATION OF PROCHIRAL OXIMES | SP PROCESS DEVELOPMENT AB (SE) | 2015-11-26 | — | — | WO | disclosed |
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |