Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321303 | 1.00 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL17134067 | 1.00 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL28530493 | 0.89 | CTSL (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL28127816 | 0.82 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL3725357 | 0.82 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| Bromobenzene SCHEMBL28232899 | 0.81 | CYP2C19 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL6815084 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL6815081 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL17008402 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL749086 | 0.78 | C1S (0.56) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574135-B | 4-aryl-5-thioether-2-difluoromethyl oxazole, and derivatives and synthesis method thereof | 湖南工程学院 | 2022-09-23 | — | — | CN | claimed |
| CN-112574135-A | 4-aryl-5-thioether-2-difluoromethyl oxazole, and derivatives and synthesis method thereof | 湖南工程学院 | 2021-03-30 | — | — | CN | claimed |
| CN-108355709-B | Application of bismuth trifluoromethanesulfonate as Beckmann rearrangement reaction catalyst | 嘉兴学院 | 2020-12-08 | — | — | CN | claimed |
| CN-110294758-A | 2- replaces 5,6- dihydro-pyrazolo [5,1- α] isoquinolin, derivative and its synthetic method | 湘潭大学 | 2019-10-01 | — | — | CN | claimed |
| CN-108355709-A | Purposes of the Bismuth triflate as Beckmann rearrangement catalyst | 嘉兴学院 | 2018-08-03 | — | — | CN | claimed |
| CN-112574135-B | 4-aryl-5-thioether-2-difluoromethyl oxazole, and derivatives and synthesis method thereof | 湖南工程学院 | 2022-09-23 | — | — | CN | disclosed |
| CN-108355709-B | Application of bismuth trifluoromethanesulfonate as Beckmann rearrangement reaction catalyst | 嘉兴学院 | 2020-12-08 | — | — | CN | disclosed |
| CN-110294758-A | 2- replaces 5,6- dihydro-pyrazolo [5,1- α] isoquinolin, derivative and its synthetic method | 湘潭大学 | 2019-10-01 | — | — | CN | disclosed |
| CN-108355709-A | Purposes of the Bismuth triflate as Beckmann rearrangement catalyst | 嘉兴学院 | 2018-08-03 | — | — | CN | disclosed |
| EP-2927218-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |
| US-9725423-B2 | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-08 | — | — | US | disclosed |
| US-9725423-B2 | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-08 | — | — | US | disclosed |
| CN-1230431-C | Arylmethylamine derivatives useful as tryptase inhibitors | AVENTIS PHARM PROD INC (US) | 2005-12-07 | — | — | CN | disclosed |
| US-20030187020-A1 | Chemical compounds | AVENTISUB LLC | 2003-10-02 | — | — | US | disclosed |
| CN-1439003-A | Arylmethylamine derivatives useful as tryptase inhibitors | AVENTIS PHARM PROD INC (US) | 2003-08-27 | — | — | CN | disclosed |
| US-6075148-A | CARBAMATE DERIVATIVES ARE USEFUL FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| US-5981532-A | FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| US-5824705-A | FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-20 | — | — | US | disclosed |
| EP-0624155-A1 | CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993015046-A1 | CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187020-A1 | Chemical compounds | CMA1, TPSB2, TPSG1 | NPC1 806/4885RAB9A 1607/4885SMN1; SMN2 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.