Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 6/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324146 | 0.82 | SCN9A (0.36) | BRD4GRM5 | |
| SCHEMBL13609250 | 0.81 | BRD4 (0.47) | CAMKK2FYNIGF1RBRD4PTGS2 | |
| SCHEMBL18902075 | 0.77 | BRD4 (0.34) | BRD4 | |
| SCHEMBL1487602 | 0.76 | BRD4 (0.56) | CAMKK2FYNIGF1RBRD4PTGS2 | |
| SCHEMBL18902127 | 0.76 | JAK2 (0.35) | TSHR | |
| SCHEMBL13745928 | 0.74 | CAMKK2 (0.41) | CAMKK2FYNIGF1RBRD4NCOA1 | |
| SCHEMBL8323355 | 0.72 | CAMKK2 (0.61) | CAMKK2IGF1R | |
| SCHEMBL1487961 | 0.69 | CAMKK2 (0.67) | CAMKK2IGF1R | |
| SCHEMBL13609200 | 0.67 | BRD4 (0.44) | CAMKK2FYNBRD4 | |
| SCHEMBL13745654 | 0.66 | BRD4 (0.55) | CAMKK2BRD4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078756-A2 | JNK INHIBITORS | EISAI CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |