Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 11/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18902075 | 0.78 | BRD4 (0.34) | BRD4 | |
| SCHEMBL18902127 | 0.77 | JAK2 (0.35) | — | |
| SCHEMBL13745655 | 0.74 | BRD4 (0.58) | SCN9ACLK1TTRBRD4FEN1 | |
| SCHEMBL8321216 | 0.74 | SCN9A (0.36) | SCN9AGRM5CLK1TTRBRD4 | |
| SCHEMBL8324896 | 0.65 | BRD4 (0.60) | SCN9AGRM5BRD4FEN1GRIN2B | |
| SCHEMBL8321050 | 0.63 | BRD4 (0.51) | SCN9AGRM5BRD4ALOX5APFEN1 | |
| SCHEMBL18098819 | 0.62 | DYRK1A (0.37) | — | |
| SCHEMBL13746314 | 0.62 | DYRK1A (0.49) | CLK1BRD4 | |
| SCHEMBL13609250 | 0.61 | BRD4 (0.47) | GRM5BRD4 | |
| SCHEMBL412228 | 0.61 | MEN1 (0.49) | TTRALOX5APFEN1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078756-A2 | JNK INHIBITORS | EISAI CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |