SCHEMBL8321933

SCHEMBL8321933

COC(=O)C(C)(C)CC(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.41
MMP8 P22894 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8211542 0.79 DGAT1 (0.38) DGAT1MMP8
SCHEMBL13788287 0.79 MMP8 (0.44) DGAT1MMP8
SCHEMBL4124393 0.77 DGAT1 (0.37) DGAT1MMP8
SCHEMBL8197896 0.76 DGAT1 (0.35) DGAT1MMP8
Ammonia Solution, Strong SCHEMBL28326930 0.76 DGAT1 (0.35) DGAT1MMP8
SCHEMBL15001408 0.76 FDPS (0.38) DGAT1MMP8
SCHEMBL276298 0.75
Ammonia Solution, Strong SCHEMBL27896704 0.75 DGAT1 (0.32) DGAT1
SCHEMBL7699120 0.74 DGAT1 (0.38) DGAT1
Hydrochloric Acid SCHEMBL11505400 0.74 DGAT1 (0.34) DGAT1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5874600-A HYDROGENATION OF AN ALKYL 3-OXO-2-ALKYLCYCLOPENTANEACETIC ACID USING A CATALYST OF A RUTHENIUM COMPLEX REACTED WITH A BIDENTATE DIPHOSPHINE LIGAND AND A NONCOORDINATING ACID; STEREOSPECIFIC; PERFUMES; HEDRONE? FIRMENICH SA (CH) 1999-02-23 US disclosed