Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641952 | 0.84 | ERN1 (0.52) | TRIM24TRIM33MCL1ALDH1A1ERN1 | |
| SCHEMBL17075433 | 0.79 | TYR (0.47) | TYRTRIM24TRIM33ALDH1A1PIK3CD | |
| SCHEMBL2800253 | 0.78 | ALDH1A1 (0.48) | TYRTRIM24TRIM33MCL1ALDH1A1 | |
| SCHEMBL3143864 | 0.78 | ALDH1A1 (0.48) | TYRMCL1ALDH1A1ERN1 | |
| SCHEMBL23754494 | 0.76 | ALDH1A1 (0.47) | MCL1ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL5776519 | 0.76 | ALDH1A1 (0.47) | TRIM24TRIM33MCL1ALDH1A1PRKDC | |
| SCHEMBL31423173 | 0.76 | ALDH1A1 (0.47) | TYRTRIM24TRIM33MCL1ALDH1A1 | |
| SCHEMBL3148643 | 0.76 | TDP1 (0.55) | TYRTRIM24TRIM33MCL1ALDH1A1 | |
| SCHEMBL18583391 | 0.75 | ALDH1A1 (0.56) | TYRTRIM24TRIM33ALDH1A1PIK3CD | |
| SCHEMBL17075432 | 0.74 | TYR (0.50) | TYRTRIM24TRIM33ALDH1A1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |