SCHEMBL17075432

SCHEMBL17075432

CCC(C)Sc1ccc(C=O)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.50
TRIM24 O15164 2/20 0.42
TRIM33 Q9UPN9 2/20 0.42
APLNR P35414 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.36
GAA P10253 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
PIK3CB P42338 1/20 0.34
PIK3CG P48736 1/20 0.34
PRKDC P78527 1/20 0.34
ERN1 O75460 4/20 0.33
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17075433 0.77 TYR (0.47) TYRTRIM24TRIM33PIK3CDPIK3CA
SCHEMBL8322156 0.74 TYR (0.52) TYRTRIM24TRIM33PIK3CDPIK3CA
SCHEMBL5324218 0.73 ALDH1A1 (0.50) TYRTDP1TSHRALDH1A1HPGD
SCHEMBL1527109 0.72 TYR (0.69) TYRTRIM24TRIM33TSHRGAA
SCHEMBL23212916 0.71 TYR (0.39) TYRTRIM24TRIM33TSHRPIK3CD
SCHEMBL9856484 0.70 ESR1 (0.45) TDP1TSHRMEN1KMT2AUSP2
SCHEMBL15659421 0.68 ACHE (0.42) TSHRGAAMEN1KMT2AALDH1A1
SCHEMBL10606250 0.68 TYR (0.49) TYRTRIM24TRIM33TDP1GAA
SCHEMBL1527080 0.67 TRPA1 (0.57) TYRTRIM24TRIM33GAAPIK3CD
Chamaecin SCHEMBL676459 0.67 TYR (1.00) TYRTRIM24TRIM33TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9951034-B2 3-ketocoumarines for LED photocuring IGM RESINS ITALIA S.R.L. (IT) 2018-04-24 US disclosed
CN-104755507-B 3-ketocoumarins for LED photocuring 意大利艾坚蒙树脂有限公司 2017-10-03 CN disclosed
US-20150259316-A1 3-KETOCOUMARINES FOR LED PHOTOCURING ELIOS S.R.L. (IT) 2015-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259316-A1 3-KETOCOUMARINES FOR LED PHOTOCURING KDM3A, KMO, HCCS TYR 210/4885TRIM24 3599/4885TRIM33 1933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.