SCHEMBL17075433

SCHEMBL17075433

CCSc1ccc(C=O)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.47
TRIM24 O15164 2/20 0.47
TRIM33 Q9UPN9 2/20 0.47
ALDH1A1 P00352 1/20 0.40
ERN1 O75460 5/20 0.39
PIK3CD O00329 1/20 0.37
PIK3CA P42336 1/20 0.37
PIK3CB P42338 1/20 0.37
PIK3CG P48736 1/20 0.37
PRKDC P78527 1/20 0.37
TYMS P04818 1/20 0.37
CDK1 P06493 1/20 0.35
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
SLC6A4 P31645 1/20 0.33
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2798653 0.80 ALDH1A1 (0.41) ALDH1A1TYMSMAPTSLC6A4PTGS2
SCHEMBL8322156 0.79 TYR (0.52) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL16706976 0.79 LMNA (0.46) ALDH1A1ERN1PRKDCTYMSPOLB
SCHEMBL17075432 0.77 TYR (0.50) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL27001987 0.76 ALDH1A1 (0.54) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL23212916 0.76 TYR (0.39) TYRTRIM24TRIM33ALDH1A1PIK3CD
SCHEMBL1546644 0.75 LMNA (0.50) ALDH1A1ERN1POLBMAPT
SCHEMBL7818843 0.74 ALDH1A1 (0.48) ALDH1A1ERN1PRKDCMAPT
Alcohol SCHEMBL28467995 0.73 ERN1 (0.58) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL1527080 0.72 TRPA1 (0.57) TYRTRIM24TRIM33ALDH1A1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9951034-B2 3-ketocoumarines for LED photocuring IGM RESINS ITALIA S.R.L. (IT) 2018-04-24 US disclosed
US-20150259316-A1 3-KETOCOUMARINES FOR LED PHOTOCURING ELIOS S.R.L. (IT) 2015-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259316-A1 3-KETOCOUMARINES FOR LED PHOTOCURING KDM3A, KMO, HCCS TYR 210/4885TRIM24 3599/4885TRIM33 1933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.