Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 7/20 | 0.51 |
| ▸ | NR0B2 | Q15466 | 3/20 | 0.51 |
| ▸ | RARA | P10276 | 6/20 | 0.50 |
| ▸ | RARG | P13631 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167076 | 0.84 | RARB (0.60) | RARBPTPN11NR0B2RARARARG | |
| SCHEMBL8522832 | 0.83 | RARB (0.52) | RARBPTPN11NR0B2RARARARG | |
| SCHEMBL8320658 | 0.79 | RARB (0.52) | RARBPTPN11NR0B2RARARARG | |
| SCHEMBL8397774 | 0.79 | MEN1 (0.43) | RARBPTPN11NR0B2RARARARG | |
| SCHEMBL6428471 | 0.74 | RARB (0.38) | RARBPTPN11RARARARG | |
| SCHEMBL8522835 | 0.74 | HSD17B10 (0.39) | RARBPTPN11NR0B2RARARARG | |
| SCHEMBL8319268 | 0.74 | MEN1 (0.68) | RARBPTPN11NR0B2RARARARG | |
| SCHEMBL14003300 | 0.74 | RARB (0.71) | RARBPTPN11NR0B2RARARARG | |
| SCHEMBL8394929 | 0.73 | RARA (0.45) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL7224464 | 0.73 | RARB (0.45) | RARBRARARARGKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | claimed |
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | disclosed |