Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.52 |
| ▸ | RARA | P10276 | 7/20 | 0.50 |
| ▸ | RARG | P13631 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322245 | 0.83 | RARB (0.52) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL9167076 | 0.77 | RARB (0.60) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL7744702 | 0.75 | RARB (0.58) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL6428605 | 0.74 | RARB (0.34) | RARBRARARARGKDM4EALDH1A1 | |
| SCHEMBL14003300 | 0.74 | RARB (0.71) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL8320658 | 0.72 | RARB (0.52) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL8690742 | 0.72 | RARB (0.49) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL2390934 | 0.71 | RARB (0.73) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL2390928 | 0.71 | RARB (0.73) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL2405337 | 0.70 | RARB (0.80) | RARBRARARARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | disclosed |