Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.36 |
| ▸ | NR0B2 | Q15466 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 3/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322245 | 0.74 | RARB (0.52) | HSD17B10RARBPTPN11NR0B2RARA | |
| SCHEMBL9161924 | 0.70 | RARA (0.47) | HSD17B10RARBRARARARGMEN1 | |
| SCHEMBL8149907 | 0.69 | KDM4E (0.45) | RARBRARARARGSERPINE1EPHX2 | |
| SCHEMBL8522832 | 0.65 | RARB (0.52) | HSD17B10RARBPTPN11NR0B2RARA | |
| SCHEMBL15200898 | 0.65 | PTPN11 (0.65) | RARBPTPN11NR0B2RARARARG | |
| SCHEMBL5834020 | 0.65 | KDM4E (0.51) | HSD17B10SERPINE1MAPTKMT2AEPHX2 | |
| SCHEMBL15766044 | 0.65 | SELL (0.47) | HSD17B10RARBRARARARGSERPINE1 | |
| SCHEMBL18040210 | 0.65 | SELL (0.47) | HSD17B10RARBRARARARGSERPINE1 | |
| SCHEMBL4553304 | 0.64 | HNF4A (0.51) | HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL18040209 | 0.63 | KDM4E (0.49) | HSD17B10RARBRARARARGSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | disclosed |