Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406394 | 0.77 | TDP1 (0.51) | L3MBTL1RAB9ATSHRCASP3SENP8 | |
| SCHEMBL8323690 | 0.77 | NPC1 (0.40) | HCRTR1HCRTR2NPC1RAB9ADHODH | |
| SCHEMBL9615079 | 0.75 | ALDH1A1 (0.52) | ATMALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9132567 | 0.73 | ALDH1A1 (0.45) | PRKCZPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8325580 | 0.72 | ALDH1A1 (0.38) | PRKCZJMJD6NPC1RAB9APOLB | |
| SCHEMBL9754362 | 0.72 | ALDH1A1 (0.48) | ATMALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8323688 | 0.72 | CSNK2A1 (0.38) | HCRTR1HCRTR2L3MBTL1NPC1ATM | |
| SCHEMBL8323952 | 0.71 | HCRTR1 (0.42) | HCRTR1HCRTR2L3MBTL1LMNAKDM4E | |
| SCHEMBL8325574 | 0.71 | KMT2A (0.34) | HCRTR1HCRTR2L3MBTL1NPC1TSHR | |
| SCHEMBL8897258 | 0.71 | ALDH1A1 (0.47) | HCRTR1LMNAALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752424-B1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5877120-A | Nicotinic acid derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0752424-A1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-01-08 | — | — | EP | disclosed |