Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323688 | 0.88 | CSNK2A1 (0.38) | NPC1MAPTAHRRAB9ASMN1; SMN2 | |
| SCHEMBL8325574 | 0.84 | KMT2A (0.34) | NPC1MAPTKMOEDNRBEDNRA | |
| SCHEMBL8325580 | 0.83 | ALDH1A1 (0.38) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9163080 | 0.79 | DHODH (0.38) | NPC1MAPTAHRRAB9ASMN1; SMN2 | |
| SCHEMBL8323952 | 0.78 | HCRTR1 (0.42) | HCRTR1HCRTR2KDM4E | |
| SCHEMBL9164765 | 0.78 | DHODH (0.39) | NPC1MAPTAHRRAB9ASMN1; SMN2 | |
| SCHEMBL8322330 | 0.77 | PRKCZ (0.40) | NPC1RAB9ASMN1; SMN2DHODHHCRTR1 | |
| SCHEMBL8959297 | 0.74 | DHODH (0.44) | DHODH | |
| SCHEMBL8809985 | 0.72 | KDM4E (0.49) | KDM4E | |
| SCHEMBL9164741 | 0.70 | CNR1 (0.40) | NPC1MAPTRAB9ASMN1; SMN2EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752424-B1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5877120-A | Nicotinic acid derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0752424-A1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-01-08 | — | — | EP | disclosed |