Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323945 | 0.88 | HCRTR1 (0.41) | HCRTR1HCRTR2LMNACRHBPKMT2A | |
| SCHEMBL8323690 | 0.78 | NPC1 (0.40) | HCRTR1HCRTR2KDM4E | |
| SCHEMBL9464752 | 0.76 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL9754376 | 0.73 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL8322330 | 0.71 | PRKCZ (0.40) | HCRTR1HCRTR2LMNAKMT2AL3MBTL1 | |
| SCHEMBL8435724 | 0.70 | KDM4E (0.53) | HCRTR1HCRTR2LMNAKMT2AL3MBTL1 | |
| SCHEMBL8323070 | 0.68 | MAPT (0.42) | HCRTR1HCRTR2LMNAKMT2AL3MBTL1 | |
| SCHEMBL8810479 | 0.68 | ALDH1A1 (0.53) | HCRTR1HCRTR2KMT2AL3MBTL1KDM4E | |
| SCHEMBL8323688 | 0.67 | CSNK2A1 (0.38) | HCRTR1HCRTR2LMNAKMT2AL3MBTL1 | |
| SCHEMBL8809985 | 0.65 | KDM4E (0.49) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752424-B1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5877120-A | Nicotinic acid derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0752424-A1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-01-08 | — | — | EP | disclosed |