Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850652 | 0.83 | EDNRA (0.47) | EDNRBEDNRA | |
| SCHEMBL7327716 | 0.82 | DHPS (0.45) | EDNRBEDNRA | |
| SCHEMBL4066610 | 0.81 | EDNRB (0.56) | EDNRBEDNRA | |
| SCHEMBL5764472 | 0.78 | EDNRB (0.62) | EDNRBEDNRA | |
| SCHEMBL5107783 | 0.76 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL7699473 | 0.72 | ALDH1A1 (0.48) | — | |
| SCHEMBL8472793 | 0.70 | TSHR (0.53) | — | |
| SCHEMBL21611480 | 0.67 | SMN1; SMN2 (0.56) | — | |
| SCHEMBL15730502 | 0.66 | L3MBTL1 (0.41) | — | |
| SCHEMBL25219606 | 0.66 | MAOB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| US-5541186-A | ENDOTHELIN RECEPTOR INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |