Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 11/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 11/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014091 | 1.00 | TOP2A (0.41) | TOP2ATOP2BHDAC1LMNAALDH1A1 | |
| SCHEMBL7012172 | 0.91 | TOP2A (0.52) | TOP2ATOP2BLMNAALDH1A1HTT | |
| SCHEMBL8323507 | 0.90 | KMT2A (0.42) | HDAC1LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL7008238 | 0.90 | KMT2A (0.42) | HDAC1LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL8319527 | 0.86 | TOP2A (0.46) | TOP2ATOP2BALDH1A1HPGDKDM4E | |
| SCHEMBL8319531 | 0.86 | TOP2A (0.46) | TOP2ATOP2BALDH1A1HPGDKDM4E | |
| SCHEMBL7008348 | 0.85 | ALDH1A1 (0.47) | HDAC1LMNAALDH1A1HTTHPGD | |
| SCHEMBL7012150 | 0.84 | KDM4E (0.46) | TOP2ATOP2BHDAC1LMNAALDH1A1 | |
| SCHEMBL7013315 | 0.84 | TOP2A (0.61) | TOP2ATOP2BLMNAALDH1A1HTT | |
| SCHEMBL7006571 | 0.83 | TOP2A (0.51) | TOP2ATOP2BLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |