Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323364 | 0.81 | CHRM3 (0.50) | ALDH1A1L3MBTL1LMNANPC1RAB9A | |
| SCHEMBL9813594 | 0.80 | ALDH1A1 (0.74) | ALDH1A1HPGDKDM4EKMT2AL3MBTL1 | |
| SCHEMBL8327647 | 0.80 | NPC1 (0.61) | ALDH1A1HPGDKMT2AL3MBTL1LMNA | |
| SCHEMBL8321112 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AL3MBTL1 | |
| SCHEMBL10401087 | 0.78 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4EKMT2AL3MBTL1 | |
| SCHEMBL5988783 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EKMT2AL3MBTL1 | |
| SCHEMBL21861227 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EKMT2AL3MBTL1 | |
| SCHEMBL9813593 | 0.78 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4EKMT2AL3MBTL1 | |
| SCHEMBL10879439 | 0.78 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4EKMT2AL3MBTL1 | |
| SCHEMBL10959203 | 0.77 | HPGD (0.78) | ALDH1A1HPGDKDM4EKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977170-A | HIGH DENISTY LIPOPROTEINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| WO-1998057927-A1 | ELEVATION OF HDL CHOLESTEROL BY 4-[(AMINOTHIOXOMETHYL)HYDRAZONO]-4-ARYLBUTYL CARBAMATES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |