Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609768 | 0.81 | CYP1A2 (0.63) | CHRM3CHRM2CHRM1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8323008 | 0.81 | ALDH1A1 (0.58) | L3MBTL1LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL8327647 | 0.81 | NPC1 (0.61) | L3MBTL1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL17856291 | 0.78 | CHRM3 (0.59) | CHRM3CHRM2CHRM1HTTL3MBTL1 | |
| SCHEMBL8325863 | 0.78 | CHRM3 (0.51) | CHRM3CHRM2CHRM1L3MBTL1LMNA | |
| SCHEMBL17847478 | 0.77 | CHRM3 (0.53) | CHRM3CHRM2CHRM1ALDH1A1 | |
| SCHEMBL5475717 | 0.75 | PTPN1 (0.62) | CHRM3CHRM2CHRM1L3MBTL1KCNQ2 | |
| SCHEMBL17847445 | 0.74 | CHRM3 (0.55) | CHRM3CHRM2CHRM1ALDH1A1 | |
| SCHEMBL19713007 | 0.74 | CHRM3 (0.52) | CHRM3CHRM2CHRM1ALDH1A1 | |
| SCHEMBL8319913 | 0.73 | LMNA (0.54) | HTTL3MBTL1LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977170-A | HIGH DENISTY LIPOPROTEINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| WO-1998057927-A1 | ELEVATION OF HDL CHOLESTEROL BY 4-[(AMINOTHIOXOMETHYL)HYDRAZONO]-4-ARYLBUTYL CARBAMATES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |