Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | PYGM | P11217 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327903 | 0.93 | DRD4 (0.42) | DRD4FAAHCACNA1GSIGMAR1CCR3 | |
| SCHEMBL8327988 | 0.91 | DRD4 (0.39) | DRD4SIGMAR1MEN1KMT2A | |
| SCHEMBL8327273 | 0.90 | DRD4 (0.40) | DRD4FAAHCACNA1GSIGMAR1CCR3 | |
| SCHEMBL8323147 | 0.89 | DRD4 (0.39) | DRD4FAAHCACNA1GSIGMAR1CCR3 | |
| SCHEMBL8328890 | 0.84 | DRD4 (0.41) | DRD4FAAH | |
| SCHEMBL8327102 | 0.81 | DRD4 (0.41) | DRD4SIGMAR1 | |
| SCHEMBL8327984 | 0.81 | DRD4 (0.39) | DRD4SIGMAR1MEN1KMT2A | |
| SCHEMBL8326299 | 0.80 | DRD4 (0.38) | DRD4FAAHCNR2 | |
| SCHEMBL8324850 | 0.79 | DRD4 (0.38) | DRD4FAAHSIGMAR1 | |
| SCHEMBL8329982 | 0.63 | DRD4 (0.46) | DRD4CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |