Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328890 | 0.91 | DRD4 (0.41) | DRD4KAT2BFAAHLMNAGAA | |
| SCHEMBL8327102 | 0.88 | DRD4 (0.41) | DRD4LMNAGAAMAPTMAPK8 | |
| SCHEMBL8327988 | 0.88 | DRD4 (0.39) | DRD4LMNAGAAMAPTMAPK8 | |
| SCHEMBL8327984 | 0.88 | DRD4 (0.39) | DRD4KAT2BLMNAGAAMAPT | |
| SCHEMBL8324935 | 0.86 | DRD4 (0.38) | DRD4BCHELMNAGAAMAPT | |
| SCHEMBL8325449 | 0.83 | DRD4 (0.42) | DRD4FAAHBCHECHRM1 | |
| SCHEMBL8327903 | 0.82 | DRD4 (0.42) | DRD4CNR2FAAH | |
| SCHEMBL8324850 | 0.80 | DRD4 (0.38) | DRD4FAAHBCHECHRM1GAA | |
| SCHEMBL8323149 | 0.80 | DRD4 (0.40) | DRD4CNR2FAAH | |
| SCHEMBL8327273 | 0.80 | DRD4 (0.40) | DRD4FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |