Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328890 | 0.93 | DRD4 (0.41) | DRD4GAALMNAMAPTDRD2 | |
| SCHEMBL8327984 | 0.92 | DRD4 (0.39) | DRD4GAALMNAMAPTDRD3 | |
| SCHEMBL8327273 | 0.91 | DRD4 (0.40) | DRD4MAPTDRD2DRD3SIGMAR1 | |
| SCHEMBL8324935 | 0.91 | DRD4 (0.38) | DRD4GAALMNAMAPTDRD2 | |
| SCHEMBL8327988 | 0.90 | DRD4 (0.39) | DRD4GAALMNAMAPTDRD3 | |
| SCHEMBL8326299 | 0.88 | DRD4 (0.38) | DRD4GAALMNAMAPTMAPK8 | |
| SCHEMBL8325449 | 0.84 | DRD4 (0.42) | DRD4DRD2DRD3SIGMAR1 | |
| SCHEMBL8324850 | 0.84 | DRD4 (0.38) | DRD4GAADRD2DRD3SIGMAR1 | |
| SCHEMBL8327903 | 0.84 | DRD4 (0.42) | DRD4DRD2DRD3SIGMAR1 | |
| SCHEMBL8323147 | 0.83 | DRD4 (0.39) | DRD4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |