Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.74 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.74 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.74 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.74 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.63 |
| ▸ | CDK1 | P06493 | 1/20 | 0.63 |
| ▸ | CDK4 | P11802 | 1/20 | 0.63 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.63 |
| ▸ | CCND1 | P24385 | 1/20 | 0.63 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352270 | 1.00 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL8323198 | 0.88 | PTGER4 (0.94) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL8323200 | 0.88 | PTGER4 (0.94) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL19651747 | 0.85 | PTGER4 (0.70) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL7770104 | 0.85 | PTGER4 (0.70) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL27919653 | 0.85 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL10870470 | 0.85 | PTGER1 (0.54) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL10870465 | 0.85 | PTGER1 (0.54) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL27746895 | 0.84 | PTGER1 (0.72) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL27746894 | 0.84 | PTGER1 (0.72) | PTGER4PTGER2PTGER3PTGER1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221559-A1 | BENZODIAZEPINES AS HCV INHIBITORS | BONFANTI JEAN-FRANCOIS | 2009-09-03 | — | — | US | disclosed |
| US-20090221559-A1 | BENZODIAZEPINES AS HCV INHIBITORS | BONFANTI JEAN-FRANCOIS | 2009-09-03 | — | — | US | disclosed |
| WO-2007026024-A2 | BENZODIAZEPINES AS HCV INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-03-08 | — | — | WO | disclosed |
| EP-0177222-B1 | CYCLOHEXANE-1,3-DIONE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PROCESSES FOR PREPARING THEM, AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1990-06-27 | — | — | EP | disclosed |
| US-4604128-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1986-08-05 | — | — | US | disclosed |
| EP-0177222-A1 | Cyclohexane-1,3-dione derivatives, compositions containing them, processes for preparing them, and their use as herbicides and plant growth regulators | ICI AUSTRALIA LIMITED (AU) | 1986-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221559-A1 | BENZODIAZEPINES AS HCV INHIBITORS | GABRA5, GABRA4, GABRA3 | PTGER4 2366/4885PTGER2 2989/4885PTGER3 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.