Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940842 | 0.98 | ALDH1A1 (0.49) | ALDH1A1MAPTALDH1A3HTR3EHTR3B | |
| SCHEMBL6240310 | 0.83 | HTR3E (0.68) | MAPTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8321228 | 0.83 | AKR1C3 (0.49) | ALDH1A1MAPTHTR3EHTR3BHTR3A | |
| Bromide SCHEMBL6773601 | 0.82 | HTR3E (0.66) | MAPTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5701472 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTALDH1A3HTR3EHTR3B | |
| SCHEMBL9830402 | 0.79 | MAPT (0.63) | ALDH1A1MAPTALDH1A3HTR3EHTR3B | |
| SCHEMBL2277814 | 0.77 | TDP1 (0.54) | ALDH1A1MAPTALDH1A3HTR3EHTR3B | |
| SCHEMBL14320628 | 0.77 | MAPT (0.59) | ALDH1A1MAPTALDH1A3HTR3EHTR3B | |
| SCHEMBL2938046 | 0.76 | SMPD3 (0.47) | ALDH1A1MAPTHTR3EHTR3BHTR3A | |
| SCHEMBL17659019 | 0.76 | KMT2A (0.42) | ALDH1A1MAPTUSP2MAOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |