Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322990 | 0.76 | HSP90AA1 (0.42) | HSP90AA1ESR1ESR2CA2CA4 | |
| SCHEMBL8458358 | 0.69 | HSP90AA1 (0.37) | HSP90AA1ALOX15 | |
| SCHEMBL10834800 | 0.68 | HSP90AA1 (0.42) | HSP90AA1 | |
| SCHEMBL1508 | 0.68 | HSP90AA1 (0.55) | HSP90AA1ESR1CA2CA4CA5A | |
| SCHEMBL8320896 | 0.68 | HSP90AA1 (0.42) | HSP90AA1ESR1ESR2CA2CA4 | |
| SCHEMBL23757992 | 0.67 | HSP90AA1 (0.48) | HSP90AA1ESR1ESR2CA2CA4 | |
| SCHEMBL814 | 0.67 | HSP90AA1 (0.59) | HSP90AA1ESR1CA2CA4CA5A | |
| SCHEMBL7522374 | 0.67 | HSP90AA1 (0.59) | HSP90AA1ESR1CA2CA4CA5A | |
| SCHEMBL13282866 | 0.65 | HSP90AA1 (0.36) | HSP90AA1 | |
| SCHEMBL9837833 | 0.64 | HSP90AA1 (0.50) | HSP90AA1CA2CA4CA5AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856558-A | REACTING 2-FORMYL- OR 2-OXOALKYLIDENETRIPHENYLPHOSPHORANE WITH A CHLORINATING AGENT; HEATING; THEN NUCLEOPHILIC AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |
| CN-1141299-A | Process for prepn. of novel stabilized phosphorus ylides | HOECHST AG (DE) | 1997-01-29 | — | — | CN | disclosed |
| EP-0741138-A2 | Process for the preparation of novel stabilised phosphorus ylides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-06 | — | — | EP | disclosed |