Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320920 | 0.74 | KMT2A (0.43) | HSP90AA1KMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL8649310 | 0.73 | HSP90AA1 (0.37) | HSP90AA1KMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL8323499 | 0.69 | HSP90AA1 (0.42) | HSP90AA1ALOX15 | |
| SCHEMBL8322990 | 0.69 | HSP90AA1 (0.42) | HSP90AA1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13282866 | 0.62 | HSP90AA1 (0.36) | HSP90AA1 | |
| SCHEMBL1508 | 0.62 | HSP90AA1 (0.55) | HSP90AA1KMT2AL3MBTL1ALDH1A1USP2 | |
| Triphenylphosphine Oxide SCHEMBL1873876 | 0.62 | KMT2A (0.50) | KMT2AL3MBTL1MEN1ALDH1A1USP2 | |
| SCHEMBL4968872 | 0.62 | CA2 (0.43) | HSP90AA1KMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL23757992 | 0.61 | HSP90AA1 (0.48) | HSP90AA1KMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL7522374 | 0.61 | HSP90AA1 (0.59) | HSP90AA1KMT2AMEN1ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808129-A | Process for the preparation of novel stabilized phosphorus ylides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | claimed |
| US-5856558-A | REACTING 2-FORMYL- OR 2-OXOALKYLIDENETRIPHENYLPHOSPHORANE WITH A CHLORINATING AGENT; HEATING; THEN NUCLEOPHILIC AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |
| US-5808129-A | Process for the preparation of novel stabilized phosphorus ylides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0741138-A2 | Process for the preparation of novel stabilised phosphorus ylides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-06 | — | — | EP | disclosed |