Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323537 | 0.81 | PIM1 (0.41) | KMT2ADRD3ALDH1A1PRKD3PIM1 | |
| SCHEMBL8320413 | 0.74 | LMNA (0.41) | KMT2APRKD3PIM1GSK3AGSK3B | |
| SCHEMBL8326003 | 0.72 | KMT2A (0.33) | KMT2AALDH1A1PRKD3PIM1GSK3A | |
| SCHEMBL9522528 | 0.71 | PIM1 (0.39) | KMT2APRKD3PIM1GSK3AGSK3B | |
| SCHEMBL10976694 | 0.70 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8136624 | 0.69 | KMT2A (0.35) | KMT2AALDH1A1 | |
| SCHEMBL10744715 | 0.68 | ALDH1A1 (0.44) | KMT2AALDH1A1PIM1GSK3APIM3 | |
| SCHEMBL9568448 | 0.68 | PIM1 (0.37) | KMT2ADRD3ALDH1A1PRKD3PIM1 | |
| SCHEMBL9568395 | 0.67 | KDM4E (0.44) | KMT2AALDH1A1 | |
| SCHEMBL9523354 | 0.66 | PRKD3 (0.48) | KMT2ADRD3ALDH1A1PRKD3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0721948-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| EP-0721948-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |