Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 8/20 | 0.39 |
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.36 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323537 | 0.89 | PIM1 (0.41) | PIM1GSK3APIM3GSK3BPRKD3 | |
| SCHEMBL10972852 | 0.88 | PIM1 (0.40) | PIM1GSK3APIM3GSK3BPRKD3 | |
| SCHEMBL10744715 | 0.83 | ALDH1A1 (0.44) | PIM1GSK3APIM3PIM2LMNA | |
| SCHEMBL9568448 | 0.81 | PIM1 (0.37) | PIM1GSK3APIM3GSK3BPRKD3 | |
| SCHEMBL9523354 | 0.79 | PRKD3 (0.48) | PIM1GSK3APIM3GSK3BPRKD3 | |
| SCHEMBL9525097 | 0.78 | PRKD3 (0.47) | PIM1GSK3APIM3GSK3BPRKD3 | |
| SCHEMBL9522977 | 0.78 | ALDH1A1 (0.54) | PIM1GSK3APIM3GSK3BPRKD3 | |
| SCHEMBL9440144 | 0.78 | TOP2A (0.37) | PIM1GSK3APIM3GSK3BPRKD3 | |
| SCHEMBL9523101 | 0.78 | LMNA (0.53) | PIM1GSK3APIM3GSK3BPRKD3 | |
| SCHEMBL9568451 | 0.78 | PIM1 (0.37) | PIM1GSK3APIM3GSK3BPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |
| US-4659734-A | BACTERICIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| EP-0058392-B1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1985-11-21 | — | — | EP | disclosed |
| EP-0058392-A1 | Substituted carboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1982-08-25 | — | — | EP | disclosed |