Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423204 | 0.82 | PARP1 (0.49) | L3MBTL1NPSR1NPC1RAB9AHPGD | |
| SCHEMBL2539492 | 0.81 | ATM (0.55) | L3MBTL1LMNAMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL8317419 | 0.78 | HPGD (0.54) | L3MBTL1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL11003334 | 0.78 | LMNA (0.78) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL9430916 | 0.76 | ATM (0.46) | L3MBTL1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9753438 | 0.76 | L3MBTL1 (0.65) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL30763329 | 0.76 | LMNA (0.65) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL29161052 | 0.76 | LMNA (0.65) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL8320891 | 0.75 | KMT2A (0.50) | LMNAKMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL845256 | 0.74 | L3MBTL1 (0.77) | L3MBTL1LMNAMAPK1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |