Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | MLNR | O43193 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624159 | 0.91 | BCHE (0.40) | DRD2DRD3BCHEACHEBACE1 | |
| SCHEMBL8620320 | 0.84 | BCHE (0.48) | DRD2DRD3BCHEACHEBACE1 | |
| SCHEMBL8622104 | 0.73 | SLC6A4 (0.44) | CACNA1G | |
| SCHEMBL4758049 | 0.72 | BCHE (0.48) | DRD2DRD3BCHEACHEBACE1 | |
| SCHEMBL8617203 | 0.72 | POLB (0.48) | — | |
| SCHEMBL8618835 | 0.71 | DRD4 (0.51) | DRD3CYP3A4DRD4 | |
| SCHEMBL8618079 | 0.69 | NCF1 (0.43) | NCF1 | |
| SCHEMBL8321870 | 0.67 | S1PR5 (0.46) | DRD2DRD3BCHEACHEBACE1 | |
| SCHEMBL8327714 | 0.67 | BCHE (0.43) | DRD2DRD3BCHEACHEBACE1 | |
| SCHEMBL8621242 | 0.66 | SPHK2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |