Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624159 | 0.88 | BCHE (0.40) | BCHEACHEBACE1DRD2DRD3 | |
| SCHEMBL8324168 | 0.84 | DRD2 (0.39) | BCHEACHEBACE1PRKAA2DRD2 | |
| SCHEMBL8622104 | 0.84 | SLC6A4 (0.44) | CACNA1G | |
| SCHEMBL8151042 | 0.76 | BCHE (0.62) | BCHEACHEBACE1SIGMAR1PRKAA2 | |
| SCHEMBL8617203 | 0.76 | POLB (0.48) | — | |
| SCHEMBL8618079 | 0.75 | NCF1 (0.43) | — | |
| SCHEMBL8618835 | 0.73 | DRD4 (0.51) | SIGMAR1DRD4DRD3 | |
| SCHEMBL8331028 | 0.72 | BCHE (0.49) | BCHEACHEBACE1SIGMAR1PRKAA2 | |
| SCHEMBL8621242 | 0.72 | SPHK2 (0.38) | — | |
| SCHEMBL8329414 | 0.71 | SIGMAR1 (0.53) | BCHEACHEBACE1SIGMAR1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |