Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075544 | 0.81 | SHBG (0.32) | SHBG | |
| SCHEMBL7122125 | 0.76 | SLC6A3 (0.41) | — | |
| SCHEMBL7128342 | 0.73 | AGL (0.30) | — | |
| SCHEMBL7126650 | 0.73 | — | — | |
| SCHEMBL6620419 | 0.73 | — | — | |
| SCHEMBL7129865 | 0.73 | SLC6A2 (0.36) | — | |
| SCHEMBL7957881 | 0.72 | EPHX1 (0.39) | EPHX1SHBGRAD52 | |
| SCHEMBL24327022 | 0.69 | SLC6A2 (0.36) | EPHX1SHBG | |
| SCHEMBL18595691 | 0.68 | ALDH1A1 (0.41) | EPHX1SHBG | |
| SCHEMBL19139659 | 0.68 | ALDH1A1 (0.41) | EPHX1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604494-B1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-28 | — | — | EP | disclosed |