Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334710 | 1.00 | ACHE (0.49) | ACHEGAACA2CA1PPARG | |
| SCHEMBL265634 | 0.85 | ACHE (0.50) | ACHEGAACA2CA1PPARG | |
| SCHEMBL14032381 | 0.83 | PPARG (0.49) | ACHEGAACA2CA1PPARG | |
| Hydrochloric Acid SCHEMBL5115047 | 0.82 | PPARG (0.47) | ACHEGAACA2CA1PPARG | |
| SCHEMBL7873221 | 0.81 | ACHE (0.50) | ACHEGAACA2CA1PPARG | |
| SCHEMBL11376872 | 0.81 | L3MBTL1 (0.42) | ACHEL3MBTL1 | |
| SCHEMBL14032377 | 0.80 | ACHE (0.51) | ACHEGAACA2CA1PPARG | |
| Hydrochloric Acid SCHEMBL5117534 | 0.79 | ACHE (0.50) | ACHEGAACA2CA1PPARG | |
| SCHEMBL9903813 | 0.79 | ACHE (0.50) | ACHEGAACA2CA1PPARG | |
| SCHEMBL8323966 | 0.78 | GAA (0.45) | ACHEGAACA2CA1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004054501-A2 | METHODS OF USIG AND COMPOSITIONS COMPRISING (-)-3-(3,4-DIMETHOXY-PHENYL)-3-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPIONAMIDE | CELGENE CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |
| WO-2004045597-A1 | METHODS OF USING AND COMPOSITIONS COMPRISING (+)-3-(3,4-DIMETHOXY-PHENYL)-3-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPIONAMIDE | CELGENE CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |