Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873221 | 0.79 | ACHE (0.50) | GAACA2ACHECA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11341490 | 0.78 | PPARG (0.57) | CA2ACHECA1ALDH1A1CYP2C19 | |
| SCHEMBL8334710 | 0.78 | ACHE (0.49) | GAACA2ACHECA1ALDH1A1 | |
| SCHEMBL8324410 | 0.78 | ACHE (0.49) | GAACA2ACHECA1ALDH1A1 | |
| SCHEMBL8060110 | 0.74 | CYP2D6 (0.55) | CYP2C19POLBLMNANPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5776514 | 0.73 | PPARG (0.50) | GAACA2ACHECA1ALDH1A1 | |
| SCHEMBL4440419 | 0.73 | NFE2L2 (0.46) | GAACA2ACHECA1ALDH1A1 | |
| SCHEMBL8204646 | 0.72 | GAA (0.58) | GAACA2ACHECA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5775200 | 0.72 | ALDH1A1 (0.46) | GAACA2ACHECA1ALDH1A1 | |
| SCHEMBL9510573 | 0.72 | ACHE (0.48) | ACHEALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045597-A1 | METHODS OF USING AND COMPOSITIONS COMPRISING (+)-3-(3,4-DIMETHOXY-PHENYL)-3-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPIONAMIDE | CELGENE CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |