Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 19/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321055 | 0.87 | ADK (0.71) | ADK | |
| SCHEMBL8975073 | 0.79 | ADK (1.00) | ADK | |
| SCHEMBL8321626 | 0.79 | ADK (0.76) | ADK | |
| 5-Iodo,5'-Deoxytubercidin SCHEMBL6236636 | 0.78 | ADK (1.00) | ADK | |
| SCHEMBL6678245 | 0.78 | ADK (1.00) | ADK | |
| 5-Iodo,5'-Deoxytubercidin SCHEMBL8331903 | 0.78 | ADK (1.00) | ADK | |
| SCHEMBL8330319 | 0.78 | ADK (1.00) | ADK | |
| SCHEMBL8324918 | 0.76 | ADK (0.58) | ADK | |
| Hydrochloric Acid SCHEMBL6234279 | 0.74 | ADK (0.77) | ADK | |
| SCHEMBL8327111 | 0.72 | ADK (0.78) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496617-B1 | Adenosine kinase inhibitors | METABASIS THERAPEUTICS INC (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5646128-A | TREATING INFLAMMATION, SEPSIS, SEPTIC SHOCK, BURNS | GENSIA, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1992012718-A1 | ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| EP-0496617-A1 | Adenosine kinase inhibitors | GENSIA, INC. (US) | 1992-07-29 | — | — | EP | disclosed |