Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321362 | 0.91 | KDM4E (0.51) | MEN1KMT2AKDM4EDHODHPOLB | |
| SCHEMBL8717010 | 0.86 | KDM4E (0.54) | MEN1KMT2AKDM4EDHODHPOLB | |
| SCHEMBL247426 | 0.85 | LMNA (0.51) | MEN1KMT2AKDM4EDHODHPOLB | |
| SCHEMBL8324531 | 0.82 | MEN1 (0.77) | MEN1KMT2AKDM4EDHODHPOLB | |
| SCHEMBL4204786 | 0.81 | LMNA (0.64) | KDM4EDHODHPOLBSMN1; SMN2LMNA | |
| SCHEMBL27810157 | 0.75 | TSHR (0.41) | MEN1KMT2AKDM4EDHODHPOLB | |
| SCHEMBL10864298 | 0.75 | LMNA (0.52) | MEN1KMT2AKDM4EDHODHPOLB | |
| SCHEMBL10866597 | 0.75 | TP53 (0.57) | MEN1KMT2AKDM4EDHODHPOLB | |
| SCHEMBL9319078 | 0.75 | MAPT (0.57) | MEN1KMT2AKDM4EDHODHPOLB | |
| SCHEMBL27810072 | 0.74 | KMT2A (0.69) | MEN1KMT2AKDM4EDHODHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | claimed |