Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.71 |
| ▸ | DHODH | Q02127 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810072 | 0.91 | KMT2A (0.69) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL8321360 | 0.89 | KDM4E (0.69) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL18746 | 0.88 | KDM4E (0.83) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL29359819 | 0.88 | KDM4E (0.83) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL19520848 | 0.87 | MEN1 (0.73) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL374556 | 0.86 | KDM4E (0.80) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL374558 | 0.86 | KDM4E (0.80) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL7962360 | 0.86 | KDM4E (0.80) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| Potassium SCHEMBL93448 | 0.86 | KDM4E (0.80) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL30595092 | 0.86 | KDM4E (0.80) | MEN1KMT2AKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | claimed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | claimed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | claimed |
| JP-8119941-A | — | — | None | — | — | JP | disclosed |
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| JP-H08119941-A | PRODUCTION OF QUINOLINE-2-YLBENZOIC ACIDS | ASAHI GLASS CO LTD | 1996-05-14 | — | — | JP | disclosed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |