Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309752 | 0.85 | SMN1; SMN2 (0.54) | NPC1RAB9AKDM4EHSD17B10TP53 | |
| SCHEMBL4316682 | 0.83 | CYP1A2 (0.56) | NPC1RAB9AKDM4EHSD17B10TP53 | |
| SCHEMBL8324473 | 0.83 | NPC1 (0.47) | NPC1RAB9AKDM4EHSD17B10TP53 | |
| SCHEMBL16957001 | 0.81 | ALDH1A1 (0.44) | NPC1RAB9AKDM4EHSD17B10TP53 | |
| SCHEMBL7448098 | 0.79 | MEN1 (0.47) | RAB9AKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8319398 | 0.79 | CASP1 (0.42) | PARP1KDM4EHSD17B10CA1CA2 | |
| SCHEMBL4309730 | 0.78 | ALDH1A1 (0.60) | NPC1RAB9AKDM4EHSD17B10TP53 | |
| SCHEMBL7369021 | 0.78 | KDM4E (0.52) | NPC1RAB9AKDM4EHSD17B10TP53 | |
| SCHEMBL2835948 | 0.78 | PARP1 (0.55) | PARP1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL4640154 | 0.77 | GRM2 (0.44) | PARP1KDM4EALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883282-A | UREA CHEMICAL INTERMEDIATES; RICE | AMERICAN CYANAMID COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5763605-A | 3-(3-aryloxyphenyl)-1-(substituted methyl)-S-triazine-2,4,6-oxo or thiotrione herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| US-5670641-A | 3-(3-aryloxyphenyl)-1-(substituted methyl)-S-triazine-2,4,6-oxo or thiotrione herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-5654256-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| US-5604180-A | RICE CROPS | AMERICAN CYANAMID COMPANY | 1997-02-18 | — | — | US | disclosed |
| EP-0745595-A1 | 3-(3-Aryloxyphenyl)-1-(substituted methyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents | American Cyanamid Company (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5519133-A | CYCLIZATION, ALKYLATION | AMERICAN CYANAMID CO. (US) | 1996-05-21 | — | — | US | disclosed |