Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 15/20 | 0.59 |
| ▸ | CDK2 | P24941 | 15/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326575 | 0.81 | CCNA2 (0.58) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL8325671 | 0.78 | CCNA2 (0.40) | CCNA2CDK2 | |
| SCHEMBL8326420 | 0.78 | CCNA2 (0.67) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL8325285 | 0.77 | CCNA2 (0.54) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL7513198 | 0.71 | KDM4E (0.59) | CCNA2CDK2 | |
| SCHEMBL5846199 | 0.68 | KDM4E (0.52) | MERTK | |
| SCHEMBL11187544 | 0.63 | KDM4E (0.53) | MERTK | |
| SCHEMBL21161396 | 0.63 | — | — | |
| SCHEMBL14838580 | 0.62 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL15880368 | 0.62 | CCNA2 (0.39) | CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |