Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326151 | 0.80 | CYP1A2 (0.41) | CCNA2CDK2KDM4ETDP1 | |
| SCHEMBL8324679 | 0.78 | CCNA2 (0.59) | CCNA2CDK2 | |
| SCHEMBL8329431 | 0.75 | CCNA2 (0.44) | CCNA2CDK2KDM4E | |
| SCHEMBL8327052 | 0.73 | CDK2 (0.35) | CCNA2CDK2KDM4E | |
| SCHEMBL8327878 | 0.73 | CCNA2 (0.34) | CCNA2CDK2KDM4E | |
| SCHEMBL8327742 | 0.72 | CCNA2 (0.34) | CCNA2CDK2KDM4E | |
| SCHEMBL8327012 | 0.68 | CYP2A6 (0.46) | CCNA2CDK2KDM4E | |
| SCHEMBL6994369 | 0.68 | ALDH1A1 (0.41) | KDM4E | |
| SCHEMBL17893783 | 0.65 | HTR2C (0.52) | — | |
| SCHEMBL8330251 | 0.65 | DUSP10 (0.45) | CCNA2CDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | claimed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | claimed |
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |