Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 17/20 | 0.58 |
| ▸ | CDK2 | P24941 | 17/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325285 | 0.85 | CCNA2 (0.54) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL8326420 | 0.81 | CCNA2 (0.67) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL8324679 | 0.81 | CCNA2 (0.59) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL8326151 | 0.80 | CYP1A2 (0.41) | CCNA2CDK2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8327012 | 0.79 | CYP2A6 (0.46) | CCNA2CDK2DUSP10ALDH1A1CYP1A2 | |
| SCHEMBL8327915 | 0.76 | CYP2A6 (0.45) | ALDH1A1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL14172822 | 0.76 | CCNA2 (0.46) | CCNA2CDK2ALDH1A1 | |
| SCHEMBL7513198 | 0.68 | KDM4E (0.59) | CCNA2CDK2DUSP10ALDH1A1CYP1A2 | |
| SCHEMBL8325078 | 0.68 | DUSP10 (0.47) | CCNA2CDK2DUSP10ALDH1A1CYP1A2 | |
| SCHEMBL14172846 | 0.68 | CYP11B1 (0.47) | CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |