Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 17/20 | 0.67 |
| ▸ | CDK2 | P24941 | 17/20 | 0.67 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325285 | 0.85 | CCNA2 (0.54) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL8329082 | 0.84 | CCNA2 (0.48) | CCNA2CDK2 | |
| SCHEMBL8325184 | 0.81 | CCNA2 (0.62) | CCNA2CDK2 | |
| SCHEMBL8326575 | 0.81 | CCNA2 (0.58) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL8327901 | 0.81 | CCNA2 (0.46) | CCNA2CDK2 | |
| SCHEMBL8580105 | 0.79 | CCNA2 (0.44) | CCNA2CDK2 | |
| SCHEMBL8324679 | 0.78 | CCNA2 (0.59) | CCNA2CDK2CDK1CDK7CDK5 | |
| SCHEMBL8329431 | 0.78 | CCNA2 (0.44) | CCNA2CDK2 | |
| SCHEMBL8330251 | 0.75 | DUSP10 (0.45) | CCNA2CDK2DUSP10 | |
| SCHEMBL8327091 | 0.74 | CCNA2 (0.51) | CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | claimed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | claimed |
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |