⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326062 | 0.89 | HTR3A (0.30) | — | |
| SCHEMBL18069713 | 0.57 | — | — | |
| SCHEMBL2736039 | 0.57 | — | — | |
| SCHEMBL23315663 | 0.57 | — | — | |
| SCHEMBL8327550 | 0.56 | CHRM1 (0.31) | — | |
| SCHEMBL8802038 | 0.56 | HTR3A (0.30) | — | |
| SCHEMBL7438465 | 0.51 | LMNA (0.64) | — | |
| SCHEMBL7426741 | 0.51 | LMNA (0.64) | — | |
| SCHEMBL6953885 | 0.51 | LMNA (0.33) | — | |
| SCHEMBL7431051 | 0.51 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |