Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324824 | 0.91 | GAA (0.50) | HDAC3APPACHEHDAC1HDAC7 | |
| SCHEMBL8326169 | 0.86 | DYRK1A (0.54) | MEN1KMT2APDE4BGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8329578 | 0.85 | PAX8 (0.53) | MEN1KMT2APDE4BGAASMN1; SMN2 | |
| SCHEMBL8329323 | 0.82 | GAA (0.47) | MEN1KMT2APDE4BGAASMN1; SMN2 | |
| SCHEMBL8329163 | 0.81 | GAA (0.51) | POLBKMT2APDE4BGAASMN1; SMN2 | |
| SCHEMBL5726874 | 0.79 | TDP1 (0.50) | POLBTDP1MEN1USP2PABPC1 | |
| SCHEMBL8328001 | 0.78 | MELK (0.47) | POLBMEN1USP2PABPC1KMT2A | |
| SCHEMBL8328847 | 0.77 | PDE4B (0.56) | TDP1MEN1KMT2APDE4BGAA | |
| SCHEMBL8326172 | 0.76 | HDAC3 (0.43) | HDAC3APPACHEHDAC1HDAC7 | |
| SCHEMBL8329171 | 0.76 | MAPT (0.45) | POLBKMT2AMELKSMN1; SMN2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |