Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18496716 | 0.86 | MAPK1 (0.49) | MAPK1PARP1KDM4EL3MBTL1PKM | |
| SCHEMBL28835625 | 0.85 | P4HTM (0.54) | MAPK1KDM4EL3MBTL1PKMPOLB | |
| SCHEMBL2631699 | 0.83 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1PKM | |
| SCHEMBL7883731 | 0.79 | MAPK1 (0.62) | MAPK1PARP1KDM4EL3MBTL1PKM | |
| SCHEMBL507299 | 0.79 | GRM2 (0.35) | KDM4EL3MBTL1PKMPOLBALDH1A1 | |
| SCHEMBL10204398 | 0.78 | ALDH1A1 (0.45) | MAPK1PARP1KDM4EPKMALDH1A1 | |
| SCHEMBL8324962 | 0.78 | MAPK1 (0.61) | MAPK1PARP1KDM4EL3MBTL1PKM | |
| SCHEMBL16452387 | 0.78 | MAPK1 (0.53) | MAPK1PARP1KDM4EL3MBTL1PKM | |
| SCHEMBL1934998 | 0.77 | HRH3 (0.50) | L3MBTL1POLBALDH1A1NPC1RAB9A | |
| SCHEMBL1437036 | 0.76 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682964-B2 | Amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-20 | — | — | US | disclosed |
| US-9682964-B2 | Amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-20 | — | — | US | disclosed |
| US-9682964-B2 | Amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-20 | — | — | US | disclosed |
| US-20170144995-A1 | AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-25 | — | — | US | disclosed |
| US-20170144995-A1 | AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-25 | — | — | US | disclosed |
| US-20170144995-A1 | AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-25 | — | — | US | disclosed |
| WO-2014168052-A1 | AMIDE COMPOUND | 住友化学株式会社 (JP) | 2014-10-16 | — | — | WO | disclosed |
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144995-A1 | AMIDE COMPOUND | NAAA, AADAC, ACMSD | MAPK1 3326/4885PARP1 4794/4885KDM4E 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.