Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 3/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089775 | 0.88 | TYR (0.47) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL23815001 | 0.82 | AHR (0.44) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL13930917 | 0.82 | AHR (0.44) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL762037 | 0.77 | AHR (0.50) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL5720438 | 0.75 | AHR (0.57) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL6092073 | 0.74 | CYP2A6 (0.49) | GAAALOX15CYP2A6MAPTRAB9A | |
| SCHEMBL19180797 | 0.73 | MAOA (0.43) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL438997 | 0.73 | KIF11 (0.60) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL5720381 | 0.73 | AHR (0.55) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL8047856 | 0.73 | AHR (0.46) | USP2GAAALOX15RAD51NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067529-A1 | INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |